Statins’ CV prevention benefits both sexes
However, compared to placebo, the benefit associated with statins did not reach statistical signficance for women in two outcomes, all-cause mortality and stroke.
US researchers synthesised data from 11 trials with a total of more than 43,000 participants, finding overall that male and female users were 18–19% less likely to experience a cardiovascular event.
However all-cause mortality and stroke in women was reduced by only 8% respectively compared with 21% and 19% respectively in men.
The reason for a gender difference was uncertain, but