Stronger safety advice for IUCDs

THE TGA has strengthened the safety advice for several IUCDs, including the popular Mirena implant, in the wake of a large European study which found an increased risk of uterine perforation in new mothers.

The eight-year European Active Surveillance Study compared rates of adverse events in more than 60,000 women who used either levonorgestrel-releasing (LNG) implants or copper intrauterine devices.

While the background rate of perforation was low (0.14% for LNG implants and 0

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