Study backs metformin for insulin-resistant women

There is increasing evidence that treating patients at a preclinical stage of disease can prevent the clinical stage, says an endocrinologist who has tested metformin on overweight insulin-resistant women.

Monash University’s Professor Susan Davis has shown when given metformin daily for six months, the women improved their insulin resistance and lost an average of 2.7kg.

At the start of the double-blind placebo-controlled study, the women had a BMI of 30 to 40. There were 58 women in the metformin group, who received 850mg twice daily.