Study backs oral immunotherapy for allergies

US researchers included 63 studies with more than 5000 participants ranging in age from four to 74 years.

They found strong evidence sublingual immunotherapy improved asthma symptoms by more than 40% compared to interventions such as inhaled steroids, and more moderate evidence supporting the therapy for decreasing rhinitis and rhinoconjunctivitis symptoms triggered by grass or dust mite allergens.

No episodes of anaphylaxis were reported in any treated patients.

JAMA 2013;309:1278-88