Study cautions on clarithromycin use in COPD

The publication of the data follows a warning issued by US authorities earlier this month about another macrolide, azithromycin, and potentially fatal arrhythmias.

The Dundee researchers looked at data from two prospectively collected databases of 1300 patients admitted to hospital with acute COPD and 1600 patients admitted with community acquired pneumonia.

They found using clarithromycin for acute COPD exacerbations was associated with a 50% increased risk of cardiovascular events, and a 67% increased risk of acute coronary