Study spells out brain bleed risk on warfarin

NEWLY flagged risk factors may place elderly patients with atrial fibrillation (AF) starting on warfarin at greater risk of traumatic intracranial bleeding than previously believed, researchers say.

Dementia, anaemia, depression, anticonvulsant use and an unstable INR were among the risk factors researchers identified for intracranial bleeds, most likely from falls, in their large study of US veterans.

“[These factors] may potentially be used in patient-centred discussions about the benefits and harms of warfarin therapy in older