Study suggests more than half of IBS could be atypical allergies

Making a connection between food intake and abdominal problems can be difficult: researchers

More than half of patients with irritable bowel syndrome (IBS) may have atypical, non-IgE mediated food allergies, a study suggests.


German researchers have used confocal laser endomicroscopy (CLE) to measure real-time changes to intestinal tissue of 108 patients with IBS who were challenged via endoscope with common foods.

Seventy per cent of the patients were CLE-positive and among them, 60.5% reacted to wheat, 20% to yeast, 9.2% to milk, 6.6% to soy and 4% to egg white.

About 8% reacted to two of the food antigens.

"Much to our surprise, more