Subclinical hyperthyroidism increases risk of AF

Swiss researchers analysed data from 10 prospective cohorts totalling 52,000 people (58% women) with a median age of 59 years. SCH, defined as thyroid stimulating hormone (TSH) lower than 0.45mIU/L with normal free thyroxine, was associated with a 68% increased risk of incident AF, 29% increased risk of CHD mortality and 24% increased risk of total mortality over nearly nine years of follow-up. The highest risks of events and death occurred when TSH was lower than 0.10mIU/L.

A leading US endocrinologist commented in an accompanying editorial that the findings provided “sufficient evidence to