Test for early Alzheimer's a step closer

The bioinformatics experts from the University of Newcastle independently analysed data on 190 plasma proteins in 566 people with Alzheimer’s disease, mild cognitive impairment or normal cognition.

The data is held in the Alzheimer’s Disease Neuroimaging Initiative database, said to be the world’s most comprehensive collection.

They found that measuring a panel of 11 different proteins could distinguish people with pre-clinical Alzheimer's disease from healthy controls with 85% accuracy.

If this set of biomarkers was measured routinely in ‘at risk’ individuals it may detect changes