Testosterone points to prostate cancer risk

Low levels of free testosterone in men with prostate cancer may help predict the likelihood that their disease will progress and require treatment, research shows.

In a study of 154 prostate cancer patients under active surveillance, 54 men (35%) progressed from having low- to high-risk disease over a follow-up of about three years.

Men with free testosterone levels below a threshold of 0.45ng/dL were four times more likely to have their disease reclassified as high risk – requiring surgery or radiation therapy – compared