Toxic amylin linked to type 1 and type 2

Scientists from New Zealand and the UK have found compelling evidence that juvenile-onset diabetes and type-2 diabetes are both caused by toxic clumps formed by amylin.

The findings, based on 20 years of work in New Zealand, suggest type 1 and type 2 diabetes could both be slowed and potentially reversed by treatments that stop amylin from forming the clumps.

“We sought to advance understanding of how altered expression and aggregation of hA might link β-cell degeneration with diabetes onset and progression, by comparing phenotypes between homozygous and

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