Type 2 diabetes linked to decreased melatonin

US researchers found the association in a case-control study nested within the Nurses’ Health Study cohort.

The finding fits with previous research suggesting melatonin may have a role in glucose metabolism, the researchers said, adding melatonin receptors have been found in tissues including pancreatic islet cells.

The study found participants in the lowest category of urinary ratio of 6-sulfatoxymelatonin to creatinine had more than twice the risk of developing diabetes (self-reported) compared to participants in the highest category.