Update on MALDI-TOF

In an earlier article, we discussed a technique MALDI-TOF (Matrix Assisted Laser Desorption Time of Flight) that has revolutionised microbe identification. 

Most modern microbiology laboratories now have a MALDI-TOF machine. Accordingly, in the last few years, more experience has been obtained in the use of MALDI-TOF. This has been reviewed in a recent article.1 Strengths and weaknesses are discussed below.