Warning over antiepileptic drug in pregnancy

Pregnant women taking topiramate in combination with other antiepileptics run a much higher risk of foetal malformations, Australian neurologists warn.

Their 15-year study looked at over 1800 pregnancies exposed to antiepileptic drugs (AEDs), used as monotherapy or in combination, focusing on levetiracetam and topiramate.

Nearly 15% of pregnancies involving topiramate as part of AED polytherapy resulted in