Weigh CVD risk with NSAIDS
Answer: High doses of NSAID medicines taken for long periods of time are associated with an increased CVD risk.
Recent studies in patients taking NSAIDs with a history of CVD compared to healthy people without comorbidities show an increase in the risk of CV death, fatal and non-fatal myocardial infarction and stroke.1-7
In one large meta-analysis the increased risk of CV events exceeded 30% for most NSAIDs.7
Diclofenac in particular has