X-rays reveal raloxifene secret

Researchers have used a sophisticated nuclear imaging equipment to explain how raloxifene reduces fracture risk in people with osteoporosis while only mildly suppressing bone loss.

They used wide- and small-angle X-ray scattering to study mature male canine and human bones that had been depleted of living cells and then exposed to raloxifene ex vivo.

“Exposure of non-viable bone to raloxifene improves intrinsic toughness in canine and human cortical bone beams tested by four-point bending,” they