Natural approach to the common cold

Two of the trials were small and biased.

A Cochrane Review (2015) of 12 RCTs (N= 3720 children and adults) compared probiotics (Lactobacillus and Bifidobacterium) with placebo and demonstrated probiotics reduced episodes of acute URTI by about 47%, duration of acute URTI by about 1.89 days, antibiotic use and school absence.2 Similarly, another meta-analysis (2014) of 20 RCTs comparing probiotics with placebo found significant reduction in number of days of illness per person, illness episodes and days absent from day care, school and work.3

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