Zinc holds potential benefits for mood
Zinc is implicated in the pathophysiology of depression.
A 2013 meta-analysis of 17 randomised controlled trials (RCTs) of 1643 depressed and 804 control subjects measuring blood zinc concentrations found greater depression severity was associated with relative zinc deficiency compared with community samples, particularly in the higher-quality studies(p < .0001).1
Trials assessing the clinical effects of zinc supplementation for the treatment of depression are limited. A systematic review in