Benzodiazepines and schizophrenia

The study showed that suicide risk during antidepressant use was lowered; and there was no associated increased risk of mortality with either antidepressant use or concurrent use of two or more antipsychotics.

However, participants who took benzodiazepines had a 91% higher risk of early death, and suicide was by far the most common cause. Most deaths occurred in patients who had been taking their benzodiazepines for longer than four weeks.

Arch Gen Psychiatry 2012; 69(5):476-483