Nitroglycerin may lessen fractures
NITROGLYCERIN could be a novel treatment to increase bone mineral density (BMD) and potentially prevent fractures in postmenopausal women, according to experts.
A Canadian study of 243 postmenopausal women with lumbar spine T scores of 0 to -2.0, who were randomised to 15 mg of nitroglycerin ointment applied daily, showed significantly increased bone formation and decreased bone resorption compared with placebo after two years.
The study is the first to test the effect of nitroglycerin ointment. Results indicate that the ointment increased areal BMD at the lumbar spine, femoral neck and hip by up to 7%