Novel target for reducing flare in giant cell arteritis
An investigational monoclonal antibody that inhibits GM-CSF receptor alpha shows promise, researchers say.
Rada Rouse
Rada is clinical news editor for Australian Doctor Group.
JAK inhibitor ‘looks promising for ankylosing spondylitis’
A study shows improvements in patient pain and function with few serious adverse events, researchers say.
Steroid injections ‘don’t hasten progression of knee OA’
Patients can be reassured that the treatment will not precipitate the need for surgery, researchers say.
Methotrexate ‘might benefit’ knee OA with inflammation
The agent could be considered if usual treatment fails, researchers say after a randomised trial.
Bleeding in anticoagulated patients ‘might flag cancer’
Emerging evidence suggests patients with AF who have a bleed should probably be investigated for malignancy, cardiologists warn.
Setback for improved therapy in advanced urothelial cancer
Neither mono nor dual immune checkpoint inhibitor therapy improved survival in multi-nation study.
Postoperative radiotherapy ‘not advisable’ in advanced NSCLC
Trial findings clarify lack of benefit and increased cardiopulmonary toxicity.
New combo therapy ‘effective first line in advanced renal cancer’
The first results of the CheckMate 9ER trial show a good response rate and improved survival, researchers say.
COVID-19: Burnout rising among medical oncologists
Surveys show the profound changes to doctors’ jobs wrought by the pandemic are taking a toll.
At last, a randomised controlled trial on antihypertensives in COVID-19
The study suggests ACE inhibitors and ARBs are safe, although a leading cardiologist suggests this is 'not the last word'.
