At last, a randomised controlled trial on antihypertensives in COVID-19
AusDoc brings you the latest news from the European Society of Cardiology Congress 2020.
Patients on common antihypertensives can continue the medication even if hospitalised with COVID-19, according to the first randomised controlled trial to address the issue.
The BRACE-CORONA trial, conducted in Brazil, found there was no mortality difference between patients who continued to take ACE inhibitors or ARBs and those who ceased the medication, the European Society of Cardiology virtual congress (ESC 2020) was told this week.
Although advice, including in Australia, has been that patients should stick with the medication in the absence of contraindication, there’s been concern that ACE-2, the functional receptor for the SARS-CoV-2 virus, might upregulate in patients with COVID-19, worsening symptoms.