Ted is a 48-year-old real estate agent who presents with a sore throat that he has had for three days. He tested negative for COVID-19 on a rapid antigen test. His medical history includes depression, eczema and plantar fasciitis. Ted is an ex-smoker and does not drink alcohol. He uses sertraline 100mg daily and methylprednisolone ointment as required. 

Ted has no family history of note and no recent history of overseas travel.

Clinically, Ted looks well but has scleral icterus. He is afebrile and normotensive. He has mild pharyngitis. There is no hepatosplenomegaly and cardiorespiratory examination is unremarkable.

A provisional diagnosis of infectious mononucleosis is made and blood work is requested given the clinical jaundice.