Does milk thistle do any good?

Clinical scenario

Thanh, a 35-year-old pharmacist with chronic hepatitis B, consulted me recently.

He mentioned that he had been treating himself with a milk thistle (Silybum marianum) product and wondered what my thoughts about it were.

I knew milk thistle was commonly marketed for “liver health” and wondered what the evidence was.

Clinical question

What is the effect of milk thistle extract on