AF ‘may be an adverse consequence’ of above-average testosterone levels
Researchers say the risk of incident AF could be considered when prescribing testosterone therapy.
Circulating testosterone within the high-normal range is associated with a higher risk of incident AF in older men, according to Australian researchers.
Regardless of whether it occurred physiologically or as a result of hormonal supplementation, AF “may be an adverse consequence” of higher-than-average testosterone concentrations, the Monash University–led team said.
“The risk of AF could be considered when weighing benefits versus risks of testosterone therapy,” they wrote in eClinicalMedicine.
Their post-hoc analysis of the ASPREE (ASPirin in Reducing Events in the Elderly) study assessed the association between endogenous testosterone levels and AF among nearly 4600 men aged 70 and over.
