Allopurinol safe for gout patients with kidney disease

The drug is not linked to increased mortality in patients who also have chronic kidney disease, primary disease study shows

Treatment with allopurinol does not increase the risk of dying among patients with gout and chronic kidney disease, a study shows.

The research was carried out in the wake of two trials that had reported allopurinol was associated with a twofold increased risk for mortality in patients with renal disease but without gout..

The studies raised concern over whether such an effect could also occur among patients with both gout and renal disease, said senior researcher Dr Yuqing Zhang of Harvard Medical School, in Boston, US.