Alzheimer’s ‘virtually guaranteed’ for people who carry two copies of the APOE4 gene variant
Around 15% of those diagnosed with Alzheimer's disease carry two copies of the gene variant.
Alzheimer’s disease is virtually guaranteed for people who carry two copies of the APOE4 gene variant, a new study suggests.
Scientists have known for the last 30 years that people with the copies — making up between 2-3% of the general population or 15% of people with Alzheimer’s disease — have significantly higher risk of the neurodegenerative disorder compared with people with the most common version, known as APOE3.
