Antibiotics are no help in severe asthma: study
Antibiotic therapy in patients with severe asthma flares has been shown to provide no additional benefit, according to the results of a large retrospective US analysis in JAMA Internal Medicine.
Guidelines do not recommend antibiotics for patients hospitalised with an asthma exacerbation — unless there are clear signs of infection.
However, a previous study has suggested 41% of patients receive antibiotics on day one, says the retrospective's lead author Dr Mihaela Stefan, from the University of Massachusetts Medical School-Baystate in Springfield, Massachusetts.
In the analysis, researchers looked at more than 19,800 adults hospitalised for asthma exacerbation and treated with systemic corticosteroids between 2015 and 2016.
Forty-four per cent were started on an antibiotic during the first two days of their hospital stay.
These patients were older (median age 48), and more likely