Antidepressant study finds the sweet spot for dosing

The 20-40mg range achieves the best balance for efficacy, tolerability and acceptability
Dr Jill Gordon
Dr Jill Gordon.

Patients treated for major depression are likely to obtain optimal benefit with the lower dose range of second-generation antidepressants, a large review of published and unpublished trial data has found.

The findings, published in Lancet Psychiatry, will have clinical implications for some pharmacological treatment guidelines, the researchers say.