Any microvascular disease raises risk of amputation: study

It should be considered a systemic disorder, say researchers

Patients with microvascular disease in any part of the body have a four-fold increased risk of leg amputation compared with having no vascular disease, regardless of diabetes, a US study suggests.

And in patients with both microvascular and peripheral arterial disease (PAD), the amputation risk is more than 20 times higher, the researchers say.