Prescribing low doses of GLP-1 RAs a long-term option, Lancet study suggests

Eli Lilly has released the first study looking at what happens when patients have their dose reduced.

Endocrinologist Dr Kishani Kannangara faced a clinical predicament recently — one that is increasingly common.

Her patient, a man in his early 50s, had life-threatening obesity but was unsuitable for surgery.

Dr Kannangara initiated a GLP-1 receptor agonist (RA), increased the dose to the maximum, and saw outstanding results: 70kg of weight loss.

“It was amazing to see this turnaround,” said Dr Kannangara from the Woolcock Institute of Medical Research in Sydney.