Babies born to mums with IBD have altered gut composition

There may be in-utero transmission that affects priming of immune system: researcher

Babies of mothers with inflammatory bowel disease (IBD) have lower gut bacterial diversity and altered bacterial composition like their mothers, compared with control women and their infants, US researchers report.


Family history is the strongest risk factor for developing IBD, but the genetic loci identified so far do not fully explain its heritability. 

Some studies have suggested that mothers may be more likely than fathers to transmit IBD, but it has been unclear whether the maternal microbiome composition during pregnancy is altered in IBD and