Benzodiazepines linked to ectopic pregnancy

Doctors may need to closely monitor women on the drugs prior to conception, US researchers say
Reuters Health

Women who fill benzodiazepine prescriptions in the 90 days prior to conception have an increased risk of ectopic pregnancy, a US study suggests.

Researchers examined insurance claims data for a cohort of 1.69 million pregnancies between November 2008 and September 2015.

Overall, 1.06% of pregnancies involved women who filled two or more benzodiazepine prescriptions totalling at least a 10-day supply in the 90 days prior to conception.

Women who filled the prescriptions had an excess of 80 ectopic pregnancies per 10,000 pregnancies.