Care urged over bupropion with suicidal teens

Off-label prescribing of the drug for depression may have serious consequences, researchers say
Reuters Health
Depressed youth

Adolescents who attempt suicide by overdosing on bupropion are more likely to have a serious outcome or die than those who try it with a selective serotonin-reuptake inhibitor, a study indicates.

US researchers analysed records from the National Poison Data System from 2013-17 for more than 30,000 young people (mean age 16) coded as “suspected suicide”.