Childhood trauma does not undermine pharmacotherapy for depression: study

International researchers say their findings contradict previous studies to the contrary

Childhood trauma should not preclude patients with major depressive disorder from accessing first-line pharmacotherapy, despite previous findings to the contrary, international researchers say.

Their meta-analysis — the largest-ever on the topic — drew from 29 clinical trials involving 6830 adults treated for major depressive disorder across the globe, including Europe, North America and Australia.