Children's noses better at combating coronavirus

Cells in their nasal passage mount a stronger early immune response than in adults: study

Children's noses may be better than adults' at defending against infection because of "pre-activated" immunity against the coronavirus, a new study suggests.

Researchers analysed cellular gene expression in nasal swabs from 45 infected patients, including 24 children, and from 42 healthy individuals, including 18 children.

In epithelial and immune cells from the children's swab samples, they saw higher levels of expression of pattern recognition receptor proteins that can sense the presence of viral RNA and