Close relatives raise risk of schizophrenia eightfold

A meta-analysis has quantified the familial risk of schizophrenia for the first time

Patients who have a first­-degree relative with schizophrenia are eight times more likely to develop the disorder compared with those with no family history, a meta-analysis shows.

Mental health treatment

Researchers from the Prince of Wales Clinical School at UNSW Sydney say their findings will improve the accuracy of risk communication to patients and could even inform a ‘vulnerability index’.

Their meta-analysis is the first to quantify the familial risk of schizophrenia, drawing on data from 19 cohort and case-control studies involving