Daily antiseptic as good as antibiotics for recurrent UTI in women

Small UK study shows prophylactic methenamine hippurate is non-inferior to usual antibiotics in reducing incidence

Prophylactic antiseptic treatment of recurrent UTIs is as good as antibiotics for cutting incidence in women, a new UK study suggests.

The multicentre, open-label trial compared the effectiveness of methenamine hippurate with usual antibiotics in reducing infection recurrence in 205 women (mean age 50) with a median of six UTIs the year before.

The researchers randomly assigned participants to receive either guideline-recommended standard treatment of low-dose antibiotics or methenamine hippurate for 12 months.