Depression diagnosis at any stage of life tied to later dementia risk: study

The increased risk was seen regardless of whether depression was diagnosed in early, middle or late life, say Danish researchers.
  • News
  • HealthDay News
  • 25 July 2023

Men and women with diagnosed depression have an increased risk for dementia, according to a study in JAMA Neurology.

Dr Holly Elser, from Aarhus University in Denmark, and colleagues examined the associations between early-, middle-, and late-life depression and incident dementia in a nationwide cohort study involving Danish individuals.

Data were included from some 246,000 individuals with depression — 68% of whom were diagnosed before 60 — and nearly 1.2 million without depression.

Relative to the comparison cohort, those with depression had a 2.4-fold higher risk of dementia, regardless of whether they were diagnosed in early, middle or late life.