Depression that develops after brain injury may be distinct disease: study
Depression associated with brain injury has distinct connectivity patterns, that differ from traditional major depressive disorder, a study shows.
Noting that depression associated with traumatic brain injury (TBI) is believed to be clinically distinct from primary major depressive disorder, the authors characterised these distinctions through mapping brain network connectivity.
Neuropsychiatrist Dr Shan Siddiqi, from Harvard Medical School in Boston, and colleagues, applied precision functional mapping to resting state MRI data from five published patient cohorts.
They analysed data on 273 adults who’d been part of other research projects where they’d undergone resting-state functional MRI in the study published in Science Translational Medicine.
