Diabetes: tight control has 'diminishing returns' on CV risks

Glucose-lowering does not help long-term heart health or reduce mortality, researchers find

Intensive glucose-lowering in older patients with advanced type 2 diabetes is unlikely to confer lasting cardiovascular benefits or reduce mortality risk compared with standard treatment, a major US trial has shown.

Diabetes

Reporting on a 15-year follow-up of patients in the Veterans’ Affairs Diabetes trial (VADT), researchers said more than five years of intensive therapy did not reduce events, such as MI, stroke or cardiovascular-related death, in the long term.

“There was no evidence of a beneficial legacy effect after the period of improved glucose control,” they said.

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