Do kids need a biopsy for coeliac diagnosis?
An algorithm is just as effective for detecting the disease in some children, say researchers
A diagnosis of coeliac disease can be made without histology in a “significant number” of children, researchers in Europe say.
They evaluated the effect of implementing the 2012 European Society for Paediatric Gastroenterology, Hepatology and Nutrition guidelines and diagnostic algorithm for a coeliac disease diagnosis in 253 children in the Netherlands.
The guideline state that the gold-standard biopsy can be skipped in children who meet specific criteria.
The criteria are:
