Dopamine antagonist drugs for nausea 'linked to stroke risk'

More research is needed, however, to demonstrate a causal effect, researchers say

Antidopaminergic antiemetics widely used to treat nausea and vomiting are associated with a threefold increased risk of ischaemic stroke, a study suggests.

Associate Professor Timothy Kleinig
Associate Professor Timothy Kleinig.

The highest increased risk was observed for metopimazine and metoclopramide (3.6-fold and 3.5-fold respectively), both of which cross the blood–brain barrier and might have an effect

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