Extra antibiotic does not prevent infection in arthroplasty: study

The Australian Surgical Antibiotic Prophylaxis trial included some 4200 patients undergoing joint replacement surgery.

Adding vancomycin to antibiotic prophylaxis in patients undergoing arthroplasty does not prevent surgical site infections, shows a real-world Australian study.

In fact, the risk of infection was higher for cefazolin prophylaxis plus vancomycin in adults having knee replacement surgery, doctors report.