Faecal-microbiota transplantation is superior to 10 days of fidaxomicin or vancomycin for resolving recurrent Clostridium difficile infection, according to results from a randomised trial.

Numerous studies have shown faecal-microbiota transplantation to be more effective that vancomycin in treating recurrent C. difficile.

But the procedure has not been compared with recently developed non-absorbable oral antibiotics like fidaxomicin.

A team of US researchers compared the effects of transplant with fidaxomicin and standard-dose vancomycin in 64 patients with recurrent infection.