Heart defect risk in IVF tied to twinning

A large study backs Australia's move to single-embryo transfers, say researchers

The excess risk of congenital heart defects (CHDs) in ART-assisted pregnancies is accounted for by twinning, according to an analysis of more than half a million pregnancies.


In fact, twins, conceived artificially or not, have nearly five times higher prevalence of a CHD than singletons.

The study, published on Tuesday in JAMA Pediatrics, supports the practice of single-embryo transfers in Australia, whereas multiple-embryo transfer elsewhere has reached “epidemic” levels, write the concerned authors.

The Canadian