Heart defect risk in IVF tied to twinning
The excess risk of congenital heart defects (CHDs) in ART-assisted pregnancies is accounted for by twinning, according to an analysis of more than half a million pregnancies.
In fact, twins, conceived artificially or not, have nearly five times higher prevalence of a CHD than singletons.
The study, published on Tuesday in JAMA Pediatrics, supports the practice of single-embryo transfers in Australia, whereas multiple-embryo transfer elsewhere has reached “epidemic” levels, write the concerned authors.
The Canadian cohort study