High-dose fish oil 'ups AF risk'

The finding suggests a need for caution when prescribing omega-3 supplements, researchers say

New evidence confirms a safety signal for fish oil, showing the supplement is linked to an increased risk of developing AF.


The finding, from an updated meta-analysis, may warrant discussion with patients about the risks and benefits of omega-3 fatty acids, particularly if the therapeutic dose is higher than 1g a day, US researchers say.

Pooled data from 81,000 elderly patients in seven trials suggested high-dose omega-3s may raise the risk of AF by almost 50%.

University of Sydney lipid specialist Associate Professor David Sullivan, who was not involved in