Largest study to date backs maternal pertussis vaccination

'Blunting' in infants occurs but seems to have little clinical import, say authors

Immunisation providers can be confident that mothers vaccinated against whooping cough during pregnancy pass on high levels of protective antibodies to their newborn, according to the largest pertussis vaccine trial to date.

vax in pregnancy

The findings showed maternally transferred whooping cough antibodies persisted until babies received their own first dose at two months of age, supporting the current advice to vaccinate during pregnancy to prevent early cases in infants.

The randomised controlled trial included 687