Lithium risk-benefit in pregnancy favourable: study

Researchers emphasise dose titration, particularly in the first trimester
Pregnant woman

Lithium treatment for bipolar disorder should not be considered an absolute contraindication during pregnancy, as the risks from its use are relatively low, researchers say.

However, the international team recommends that pregnancy should be planned during remission and that lithium is prescribed within the lowest therapeutic range, particularly during the woman’s first trimester and immediately before delivery.