‘Little to no risk’ of birth defects with metformin in early pregnancy: study

The findings are 'timely and welcome', says Dr Ka-Kiu Cheung.
Rachel Fieldhouse
Dr Ka-Kiu Cheung.

Pregnant women with type 2 diabetes can safely use metformin in the first trimester, according to US epidemiologists who report no increased risk for congenital malformations or non-live births.

The Harvard University-led team say the findings suggest that current recommendations to switch from metformin to insulin during pregnancy based on teratogenicity concerns “may require reconsideration”.